Open AccessrAed a 4: A New 67-kDa <b><i>Aedes aegypti</i></b> Mosquito Salivary Allergen for the Diagnosis of Mosquito Allergy
Author(s) -
Zhikang Peng,
Caihe Li,
Andrew Beckett,
Qingdong Guan,
Anthony A. James,
F. Estelle R. Simons
Publication year - 2016
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000448587
Subject(s) - aedes aegypti , immunoglobulin e , saliva , immunology , allergen , allergy , antibody , recombinant dna , biology , medicine , larva , biochemistry , botany , gene
Accurate diagnosis of mosquito allergy has been hampered by the laborious task of obtaining mosquito salivary allergens. We have previously studied 3 recombinant (r) Aedes aegypti mosquito salivary allergens: rAed a 1, rAed a 2 and rAed a 3. Here, we report the expression, purification, identification and evaluation of rAed a 4, a 67-kDa α-glucosidase.