Open AccessMiR-139-5p is Increased in the Peripheral Blood of Patients with Prostate Cancer
Author(s) -
Cheng Pang,
Ming Liu,
Weiwei Fang,
Jun Guo,
Zhipeng Zhang,
Pengjie Wu,
Yaoguang Zhang,
JianYe Wang
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000447819
Subject(s) - prostate cancer , medicine , pathological , biomarker , hyperplasia , microrna , receiver operating characteristic , carcinogenesis , peripheral blood , oncology , cancer , prostate , area under the curve , pathology , gastroenterology , biology , gene , biochemistry
Emerging evidence suggested that microRNAs (miRNAs) play a causal role in cancer tumorigenesis. Aberrant expression of miRNA (miR)-139-5p has been observed in various types of cancers. The present study evaluated the relationship between miR-139-5p expression levels and prostate cancer (PCa), to assess the feasibility of using peripheral blood miR-139-5p as a potential non-invasive biomarker for PCa.