Serum Levels of Insulin-Like Growth Factor-1 and Obsessive-Compulsive Disorder: A Case-Control Study | Zendy

Gianluca Rosso | Zendy; Roberta Zanardini | Zendy; Daniela Francesca Chiodelli | Zendy; Clarissa Ferrari | Zendy; Massimo Gennarelli | Zendy; Luisella BocchioChiavetto | Zendy

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Serum Levels of Insulin-Like Growth Factor-1 and Obsessive-Compulsive Disorder: A Case-Control Study

Author(s) -

Gianluca Rosso,

Roberta Zanardini,

Daniela Francesca Chiodelli,

Clarissa Ferrari,

Massimo Gennarelli,

Luisella BocchioChiavetto

Publication year - 2016

Publication title -

neuropsychobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.71

H-Index - 83

eISSN - 1423-0224

pISSN - 0302-282X

DOI - 10.1159/000446918

Subject(s) - medicine , major depressive disorder , insulin like growth factor , pathogenesis , drug naïve , endocrinology , growth factor , drug , psychiatry , receptor , amygdala

Recent findings suggest an involvement of insulin-like growth factor-1 (IGF-1) in the pathogenesis of many psychiatric disorders; however, there is a lack of data regarding IGF-1 in patients with obsessive-compulsive disorder (OCD). The aims of the present study were (1) to analyze putative alterations of IGF-1 serum content in patients with OCD compared to patients with major depressive disorder (MDD) and healthy controls, and (2) to analyze putative changes of IGF-1 levels during drug treatment in subjects with OCD compared to patients with MDD.

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