Open AccessAssociation of Lactase Persistence Genotypes with High Intake of Dairy Saturated Fat and High Prevalence of Lactase Non-Persistence among the Mexican Population
Author(s) -
Claudia OjedaGranados,
Arturo Panduro,
João Renato Rebello Pinho,
Omar Ramos-López,
Ketti Gleyzer,
Fernanda de Mello Malta,
Karina González-Aldaco,
Sonia Román
Publication year - 2016
Publication title -
lifestyle genomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 30
eISSN - 2504-3188
pISSN - 2504-3161
DOI - 10.1159/000446241
Subject(s) - lactase , genotype , obesity , population , genotyping , biology , zoology , medicine , lactose , genetics , food science , endocrinology , gene , environmental health
Lactase (LCT) -13910 C>T and -22018 G>A polymorphisms associated with the lactase non-persistence (LNP)/persistence (LP) phenotypes vary globally. LP has been associated with obesity in Europeans. However, it has not been genetically evaluated in Mexico, a country with admixed population, recent introduction of dairy, and a high prevalence of obesity. Thus, we aimed to determine the distribution of the LCT polymorphisms and their association with the nutritional profile of West Mexico's populations.