Open AccessTLR4 Overexpression Inhibits Endothelial PAS Domain-Containing Protein 1 Expression in the Lower Respiratory Tract of Patients with Chronic COPD
Author(s) -
Hong Li,
Tian Yang,
Fei-Yan Li,
Qian Ning,
Zhaohui Sun
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000445659
Subject(s) - copd , bisulfite sequencing , biology , microbiology and biotechnology , tlr4 , bronchoalveolar lavage , real time polymerase chain reaction , methylation , respiratory tract , dna methylation , inflammation , immunology , pathology , cancer research , medicine , gene expression , lung , respiratory system , gene , biochemistry , anatomy
The study was designed to explore the potential relationship of TLR4 and endothelial PAS domain-containing protein 1 (EPAS1) in vivo and vitro experiments.