MiR-410 Down-Regulates the Expression of Interleukin-10 by Targeting STAT3 in the Pathogenesis of Systemic Lupus Erythematosus | Zendy

Dongmei Liu | Zendy; Na Zhang | Zendy; Xiaomei Zhang | Zendy; Muting Qin | Zendy; Youdan Dong | Zendy; Lei Jin | Zendy

Open Access

MiR-410 Down-Regulates the Expression of Interleukin-10 by Targeting STAT3 in the Pathogenesis of Systemic Lupus Erythematosus

Author(s) -

Dongmei Liu,

Na Zhang,

Xiaomei Zhang,

Muting Qin,

Youdan Dong,

Lei Jin

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000445625

Subject(s) - pathogenesis , microrna , stat3 , untranslated region , immunology , three prime untranslated region , autoimmunity , messenger rna , lupus erythematosus , interleukin , medicine , biology , signal transduction , cytokine , gene , antibody , microbiology and biotechnology , genetics

Systemic lupus erythematosus (SLE) is a heterogeneous chronic inflammatory autoimmune disorder, in the pathogenesis of which miRNAs play a versatile function. The purpose of this study was to investigate the effect of miRNA-410 on the pathogenesis of SLE in T cells of SLE patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research