TNF-α Activates High-Mobility Group Box 1 - Toll-Like Receptor 4 Signaling Pathway in Human Aortic Endothelial Cells | Zendy

Won Seok Yang | Zendy; Nam Jeong Han | Zendy; JinJu Kim | Zendy; Mee Jeong Lee | Zendy; Su-Kil Park | Zendy

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TNF-α Activates High-Mobility Group Box 1 - Toll-Like Receptor 4 Signaling Pathway in Human Aortic Endothelial Cells

Author(s) -

Won Seok Yang,

Nam Jeong Han,

JinJu Kim,

Mee Jeong Lee,

Su-Kil Park

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000445570

Subject(s) - syk , tlr4 , signal transduction , toll like receptor , microbiology and biotechnology , small interfering rna , hmgb1 , tumor necrosis factor alpha , receptor , biology , chemistry , cancer research , tyrosine kinase , transfection , immunology , cell culture , innate immune system , biochemistry , genetics

Toll-like receptor 4 (TLR4) interacts with endogenous substances as well as lipopolysaccharide. We explored whether TLR4 is implicated in tumor necrosis factor-α (TNF-α) signal transduction in human aortic endothelial cells.

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