Open AccessRisk Factors for Barrett's Oesophagus
Author(s) -
Neel Sharma,
Khek Yu Ho
Publication year - 2016
Publication title -
gastrointestinal tumors
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2296-3766
pISSN - 2296-3774
DOI - 10.1159/000445349
Subject(s) - medicine , asymptomatic , disease , incidence (geometry) , family history , gastroenterology , barrett's oesophagus , helicobacter pylori , reflux , risk factor , alcohol consumption , adenocarcinoma , cancer , alcohol , biochemistry , physics , chemistry , optics
Barrett's oesophagus (BO) is a premalignant condition associated with the development of oesophageal adenocarcinoma (OAC). Globally, the incidence of OAC is rising. Furthermore, the prognosis regarding the morbidity and mortality of OAC is bleak, with an estimated 5-year survival of 10-15%. Hence, detection of the premalignant phase is paramount. Endoscopy and biopsy sampling is the mainstay of diagnosis. Patients may present with symptoms of gastro-oesophageal reflux disease (GORD) or be completely asymptomatic. Therefore, symptomatology alone is a poor indicator of this condition.