Open AccessThe Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of the Bauhinia Championii Flavone are Connected with Protection Against Myocardial Ischemia/Reperfusion Injury
Author(s) -
Jie Jian,
Fujun Xuan,
Qin F,
Renbin Huang
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000443080
Subject(s) - tunel assay , lactate dehydrogenase , malondialdehyde , superoxide dismutase , glutathione peroxidase , pharmacology , reperfusion injury , chemistry , oxidative stress , apoptosis , terminal deoxynucleotidyl transferase , lipid peroxidation , ischemia , biochemistry , medicine , enzyme
Previous studies have demonstrated that Bauhinia championii flavone (BCF) exhibits anti-oxidative, anti-hypoxic and anti-stress properties. This study was designed to investigate whether BCF has a cardioprotective effect against myocardial ischemia/reperfusion (I/R) injuries in rats and to shed light on its possible mechanism.