Chikungunya Virus Infection Alters Expression of MicroRNAs Involved in Cellular Proliferation, Immune Response and Apoptosis | Zendy

Anuj Sharma | Zendy; Nagaraja S. Balakathiresan | Zendy; Radha K. Maheshwari | Zendy

Open Access

Chikungunya Virus Infection Alters Expression of MicroRNAs Involved in Cellular Proliferation, Immune Response and Apoptosis

Author(s) -

Anuj Sharma,

Nagaraja S. Balakathiresan,

Radha K. Maheshwari

Publication year - 2015

Publication title -

intervirology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.641

H-Index - 61

eISSN - 1423-0100

pISSN - 0300-5526

DOI - 10.1159/000441309

Subject(s) - chikungunya , biology , microrna , virus , virology , western blot , immune system , signal transduction , immunology , microbiology and biotechnology , gene , genetics

Chikungunya virus (CHIKV) is a reemerging virus of significant importance that has caused large-scale outbreaks in the countries with a temperate climate. CHIKV causes debilitating arthralgia which can persist for weeks and up to a year. Fibroblast cells are the main target of CHIKV infection. In this study, we analyzed microRNA (miRNA) modulation in the fibroblast cells infected with CHIKV at an early stage of infection.

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