Open AccessThe <b><i>MTHFR</i></b> C677T Polymorphism Is Related to Plasma Concentration of Oxidized Low-Density Lipoprotein in Adolescents with Cardiovascular Risk Factors
Author(s) -
Carla Cristina de Morais,
Maira Chiquito Alves,
Elaine Moura Augusto,
Dulcinéia Saes Parra Abdalla,
Maria Aderuza Horst,
Cristiane Cominetti
Publication year - 2015
Publication title -
lifestyle genomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 30
eISSN - 2504-3188
pISSN - 2504-3161
DOI - 10.1159/000439218
Subject(s) - methylenetetrahydrofolate reductase , medicine , endocrinology , homocysteine , chemistry , hyperhomocysteinemia , biochemistry , allele , gene
The aim of this study was to investigate possible relationships among the A1298C (rs1801131) and C677T (rs1801133) polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and levels of homocysteine, vitamins B6, B12, folic acid and lipid profile, including oxidized low-density lipoprotein (ox-LDL), of adolescents at cardiovascular risk.