Open AccessExpression of 58-kD Microspherule Protein (MSP58) is Highly Correlated with PET Imaging of Tumor Malignancy and Cell Proliferation in Glioma Patients
Author(s) -
Wei Lin,
Shuhui Dai,
Tao Chen,
Nobuyuki Kawai,
Keisuke Miyake,
Masaki Okada,
Reiji Haba,
Yuka Yamamoto,
Takashi Tamiya,
Fei Zhou
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000438656
Subject(s) - malignancy , glioma , cancer research , cell growth , medicine , positron emission tomography , protein expression , pathology , biology , nuclear medicine , gene , biochemistry , genetics
The nucleolar 58-kDa microspherule protein (MSP58) has important transcriptional regulation functions and plays a crucial role in the tumorigenesis and progression of cancers. 3'-deoxy-3'-[18F]fluorothymidine (FLT) has emerged as a promising positron emission tomography (PET) tracer for evaluating tumor malignancy and cell proliferation.