Leukotriene B4 Inhibits L-Type Calcium Channels via p38 Signaling Pathway in Vascular Smooth Muscle Cells | Zendy

Xiaoyu Liu | Zendy; Tingting Yang | Zendy; Langxi Miao | Zendy; YanAi Mei | Zendy; Changlong Hu | Zendy

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Leukotriene B4 Inhibits L-Type Calcium Channels via p38 Signaling Pathway in Vascular Smooth Muscle Cells

Author(s) -

Xiaoyu Liu,

Tingting Yang,

Langxi Miao,

YanAi Mei,

Changlong Hu

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000438551

Subject(s) - vascular smooth muscle , leukotriene b4 , t type calcium channel , calcium channel , l type calcium channel , voltage dependent calcium channel , calcium , protein kinase c , signal transduction , biology , endocrinology , microbiology and biotechnology , medicine , chemistry , inflammation , smooth muscle

Arachidonic acid (AA) and its metabolites are important endogenous lipid messengers. In this study, we test the effect of Leukotriene B4 (LTB4), a 5-lipoxygenase metabolite of AA, on L-type calcium channels in A7r5 rat aortic vascular smooth muscle cells.

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