Treatment of Acute Hepatitis C Infection with Pegylated Interferon and Ribavirin in Patients Coinfected with Human Immunodeficiency Virus: A Systematic Review and Meta-Analysis | Zendy

Bing Zhang | Zendy; Nghia Nguyen | Zendy; Brittany E. Yee | Zendy; Benjamin Hon Kei Yip | Zendy; Walid S. Ayoub | Zendy; Glen Lutchman | Zendy; Mindie H. Nguyen | Zendy

Open Access

Treatment of Acute Hepatitis C Infection with Pegylated Interferon and Ribavirin in Patients Coinfected with Human Immunodeficiency Virus: A Systematic Review and Meta-Analysis

Author(s) -

Bing Zhang,

Nghia Nguyen,

Brittany E. Yee,

Benjamin Hon Kei Yip,

Walid S. Ayoub,

Glen Lutchman,

Mindie H. Nguyen

Publication year - 2015

Publication title -

intervirology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.641

H-Index - 61

eISSN - 1423-0100

pISSN - 0300-5526

DOI - 10.1159/000437427

Subject(s) - ribavirin , medicine , gastroenterology , pegylated interferon , hepatitis c virus , hepatitis c , meta analysis , hepatitis b , virology , immunology , virus

Of the 35 million human immunodeficiency virus (HIV)-positive patients worldwide, 10-40% are coinfected with chronic hepatitis C virus (HCV). Compared to HCV-monoinfected patients, those coinfected experience decreased spontaneous HCV clearance, accelerated liver fibrosis, and a decreased response to anti-HCV therapy. We conducted a meta-analysis to estimate the efficacy of treating acute HCV in HIV-positive patients with peginterferon and ribavirin combination therapy.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research