Open AccessAutophagy Plays a Protective Role in Advanced Glycation End Product-Induced Apoptosis in Cardiomyocytes
Author(s) -
Pengfei Hu,
Hui Zhou,
Ming Lu,
Liping Dou,
Gang Bo,
Jiale Wu,
Shouqiang Huang
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430388
Subject(s) - autophagy , pi3k/akt/mtor pathway , protein kinase b , glycation , advanced glycation end product , microbiology and biotechnology , apoptosis , mapk/erk pathway , p38 mitogen activated protein kinases , chemistry , signal transduction , biology , biochemistry , receptor
To investigate the effect of advanced glycation endproduct-induced autophagy in rat cardiomyocytes and to identify the role of autophagy in advanced glycation end product-induced cell apoptosis.