Open AccessLoureirin B Inhibits Hypertrophic Scar Formation via Inhibition of the TGF-β1-ERK/JNK Pathway
Author(s) -
Ting He,
Xiaozhi Bai,
Longlong Yang,
Li Fan,
Yan Li,
Linlin Su,
Jianxin Gao,
Shichao Han,
Dahai Hu
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430385
Subject(s) - mapk/erk pathway , hypertrophic scar , scars , chemistry , p38 mitogen activated protein kinases , in vivo , ex vivo , kinase , microbiology and biotechnology , phosphorylation , in vitro , pathology , biology , medicine , biochemistry
Our previous study confirmed that Loureirin B (LB) can inhibit hypertrophic scar formation. However, the mechanism of LB-mediated inhibition of scar formation is still unknown.