Downregulation of IL6 Targeted MiR-376b May Contribute to a Positive IL6 Feedback Loop During Early Liver Regeneration in Mice | Zendy

Shan Lu | Zendy; Heng Jiao | Zendy; Juan Xu | Zendy; Yongxia Zheng | Zendy; Yimin Sun | Zendy; Huan Chen | Zendy

Open Access

Downregulation of IL6 Targeted MiR-376b May Contribute to a Positive IL6 Feedback Loop During Early Liver Regeneration in Mice

Author(s) -

Shan Lu,

Heng Jiao,

Juan Xu,

Yongxia Zheng,

Yimin Sun,

Huan Chen

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430348

Subject(s) - microrna , liver regeneration , biology , downregulation and upregulation , microbiology and biotechnology , stat3 , cell growth , gene expression profiling , apoptosis , regeneration (biology) , signal transduction , gene expression , genetics , gene

MicroRNAs (miRNAs) are a group of endogenous, small, noncoding RNAs implicated in a variety of biological processes, including cell proliferation, apoptosis, differentiation and metabolism. The present study aims to explore the potential role and molecular mechanism of miR-376b during the early phase of liver regeneration.

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