Aggravated Liver Injury but Attenuated Inflammation in PTPRO-Deficient Mice Following LPS/D-GaIN Induced Fulminant Hepatitis | Zendy

Xiaochen Wang | Zendy; Shushan Yan | Zendy; Donghua Xu | Zendy; ­Jun Li­ | Zendy; Yu Xie | Zendy; Jiajie Hou | Zendy; Runqiu Jiang | Zendy; Chuanyong Zhang | Zendy; Beicheng Sun | Zendy

Open Access

Aggravated Liver Injury but Attenuated Inflammation in PTPRO-Deficient Mice Following LPS/D-GaIN Induced Fulminant Hepatitis

Author(s) -

Xiaochen Wang,

Shushan Yan,

Donghua Xu,

Jun Li,

Yu Xie,

Jiajie Hou,

Runqiu Jiang,

Chuanyong Zhang,

Beicheng Sun

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430346

Subject(s) - tlr4 , inflammation , medicine , immunology , liver injury , immune system , innate immune system , pharmacology , biology

Critical roles of PTPRO and TLR4 have been implicated in hepatocellular carcinoma. However, little is known about their modifying effects on inflammation-related diseases in liver, particularly fulminant hepatitis (FH). We aim to investigate the potential role of PTPRO and its interaction with TLR4 in LPS/D-GaIN induced FH.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research