MicroRNA-140-5p Inhibits the Progression of Colorectal Cancer by Targeting VEGFA | Zendy

Wenbo Zhang | Zendy; Chen Zou | Zendy; Lei Pan | Zendy; Ying Xu | Zendy; Weidong Qi | Zendy; Gui Ma | Zendy; Yongzhong Hou | Zendy; Pengcheng Jiang | Zendy

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MicroRNA-140-5p Inhibits the Progression of Colorectal Cancer by Targeting VEGFA

Author(s) -

Wenbo Zhang,

Chen Zou,

Lei Pan,

Ying Xu,

Weidong Qi,

Gui Ma,

Yongzhong Hou,

Pengcheng Jiang

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000430237

Subject(s) - microrna , gene silencing , cancer research , carcinogenesis , vascular endothelial growth factor a , cell growth , colorectal cancer , biology , downregulation and upregulation , ectopic expression , tumor progression , rna interference , transfection , cell culture , cancer , rna , vascular endothelial growth factor , gene , genetics , vegf receptors

microRNAs (miRNAs) are small non-coding RNAs and have been shown to play a crucial role in the colorectal cancer (CRC) tumorigenesis and progression. The aim of this study was to investigate the clinical significance and prognostic value of miR-140-5p in CRC. The exact functions and the underlying molecular mechanisms of miR-140-5p in CRC was further determined.

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