Open AccessThe Role of Janus Kinase 3 in the Regulation of Na+/K+ ATPase under Energy Depletion
Author(s) -
Zohreh Hosseinzadeh,
Sabina Honisch,
Evi Schmid,
Kashif Jilani,
Kalina Szteyn,
Shefalee K. Bhavsar,
Yogesh Singh,
Mònica Palmada,
Anja T. Umbach,
Ekaterina Shumilina,
Florian Läng
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000430133
Subject(s) - chemistry , janus kinase 3 , ouabain , microbiology and biotechnology , atpase , biology , biochemistry , interleukin 12 , enzyme , in vitro , sodium , cytotoxic t cell , organic chemistry
Janus kinase-3 (JAK3) is activated during energy depletion. Energy-consuming pumps include the Na(+)/K(+)-ATPase. The present study explored whether JAK3 regulates Na(+)/K(+)-ATPase in dendritic cells (DCs).