Baicalin Attenuates High Fat Diet-Induced Obesity and Liver Dysfunction: Dose-Response and Potential Role of CaMKKβ/AMPK/ACC Pathway
Author(s) -
Youli Xi,
Miaozong Wu,
Hongxia Li,
Siqi Dong,
Erfei Luo,
Mingbo Gu,
Xiao Z. Shen,
Yabo Jiang,
Yaqun Liu,
Hua Liu
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000374037
Subject(s) - baicalin , ampk , fatty liver , endocrinology , medicine , steatosis , hyperlipidemia , alanine transaminase , aspartate transaminase , liver function , protein kinase a , chemistry , kinase , diabetes mellitus , biochemistry , enzyme , alkaline phosphatase , disease , high performance liquid chromatography , chromatography
Obesity-associated fatty liver disease affects millions of individuals. This study aimed to evaluate the therapeutic effects of baicalin to treat obesity and fatty liver in high fat diet-induced obese mice, and to study the potential molecular mechanisms.
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