Open AccessMicroRNA-449a Inhibits Proliferation and Induces Apoptosis by Directly Repressing E2F3 in Gastric Cancer
Author(s) -
Xiaoping Li,
Hong Li,
Rui Zhang,
Jing Liu,
Jun Liu
Publication year - 2015
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000374010
Subject(s) - microrna , cancer research , gene silencing , cancer , apoptosis , cell growth , transcription factor , biology , cell cycle , cisplatin , cancer cell , carcinogenesis , gene , chemotherapy , biochemistry , genetics
MicroRNA-449a is a tumor suppressor that is down-regulated in multiple tumors types. However, the role of miR-449a in gastric cancer (GC) remains largely unknown.
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