TNF-α- Mediated-p38-Dependent Signaling Pathway Contributes to Myocyte Apoptosis in Rats Subjected to Surgical Trauma | Zendy

Huaxing Wu | Zendy; Guonian Wang | Zendy; Shuai Li | Zendy; Mingyue Zhang | Zendy; Hulun Li | Zendy; Kun Wang | Zendy

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TNF-α- Mediated-p38-Dependent Signaling Pathway Contributes to Myocyte Apoptosis in Rats Subjected to Surgical Trauma

Author(s) -

Huaxing Wu,

Guonian Wang,

Shuai Li,

Mingyue Zhang,

Hulun Li,

Kun Wang

Publication year - 2015

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000373965

Subject(s) - apoptosis , myocyte , tunel assay , p38 mitogen activated protein kinases , tumor necrosis factor alpha , cytokine , signal transduction , medicine , endocrinology , microbiology and biotechnology , biology , mapk/erk pathway , biochemistry

The accumulation of cytokines in the plasma after trauma can induce myocyte apoptosis. We aimed to identify which cytokine(s) present in the plasma responsible for myocyte apoptosis, and delineated the signal transduction mechanism in rats subjected to surgical trauma.

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