Absence of Microsatellite Instability In Soft Tissue Sarcomas | Zendy

Nathália C. Campanella | Zendy; Valter Penna | Zendy; Guilherme Ribeiro | Zendy; Lucas Faria AbrahãoMachado | Zendy; Cristovam ScapulatempoNeto | Zendy; Rui Manuel Reis | Zendy

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Absence of Microsatellite Instability In Soft Tissue Sarcomas

Author(s) -

Nathália C. Campanella,

Valter Penna,

Guilherme Ribeiro,

Lucas Faria AbrahãoMachado,

Cristovam ScapulatempoNeto,

Rui Manuel Reis

Publication year - 2015

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000369906

Subject(s) - microsatellite instability , microsatellite , soft tissue , soft tissue sarcoma , sarcoma , biology , medicine , genetics , pathology , computational biology , allele , gene

Here, we analyze a series of soft tissue sarcomas (STS), which are a heterogeneous group of mesenchymal neoplasms, for the presence and frequency of microsatellite instability (MSI). MSI has been proposed to be clinically relevant for colorectal cancer, yet on STS its role is not consensual, partly due to the limited number of cases analyzed and methodology issues.

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