Open AccessMicroRNA-302b Suppresses Human Epithelial Ovarian Cancer Cell Growth by Targeting RUNX1
Author(s) -
Tingting Ge,
Mingzhu Yin,
Meng Yang,
Tianbo Liu,
Ge Lou
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000369664
Subject(s) - gene knockdown , ectopic expression , microrna , cancer research , gene silencing , cell growth , runx1 , biology , cell culture , chemistry , microbiology and biotechnology , stem cell , gene , biochemistry , genetics , haematopoiesis
The microRNA (miR)-302 family functions as a tumor suppressor in human cancer. However, its role in epithelial ovarian carcinoma (EOC) remains unknown. Here, we investigated the role of miR-302b and its target gene RUNX1 in EOC.