Open AccessAntibiosis of Necrotizing Pancreatitis
Author(s) -
Alexander Arlt,
Wiebke Erhart,
Clemens Schafmayer,
Hanns-Christoph Held,
Jochen Hampe
Publication year - 2014
Publication title -
visceral medicine
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2297-475X
pISSN - 2297-4725
DOI - 10.1159/000367948
Subject(s) - medicine , antibiotics , pancreatitis , intensive care medicine , acute pancreatitis , disease , antibiotic prophylaxis , surgery , microbiology and biotechnology , biology
Necrotizing pancreatitis is a life-threatening presentation of acute pancreatitis. The mortality of 20-80% initially depends on the persistence of organ failure and systemic inflammatory response syndrome (SIRS) and, in the later course of the disease, on secondary infection of the necrosis. The questions whether prophylactic antibiotics aiming to prevent this infection should be administered and which antibiotic is the best to use, as well as the problem of fungal infection under antibiotic treatment are still intriguing and insufficiently solved.