Open AccessThe Weaned Pig as a Model for Doxorubicin-Induced Mucositis
Author(s) -
Jamee Covington Martin,
Scott C. Howard,
Asha Pillai,
Peter Vogel,
Anjaparavanda P. Naren,
Steven Davis,
Karen Ringwald-Smith,
Karyl K. Buddington,
Randal K. Buddington
Publication year - 2014
Publication title -
chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.539
H-Index - 54
eISSN - 1421-9794
pISSN - 0009-3157
DOI - 10.1159/000365725
Subject(s) - mucositis , colostrum , medicine , diarrhea , gastroenterology , chemotherapy , immunology , antibody
Chemotherapy-induced mucositis (CIM) complicates cancer therapy and limits maximum tolerated doses and efficacy. Rodent models do not reproducibly mimic clinical CIM, so alternative models are needed.