Open AccessComposite Paraganglioma and Neuroblastoma of the Urinary Bladder: A Rare Histopathological Entity
Author(s) -
Evan Lacefield,
Omer Raheem,
Roni Cox,
Rodney Davis,
Mohamed H. Kamel
Publication year - 2015
Publication title -
current urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.476
H-Index - 13
eISSN - 1661-7657
pISSN - 1661-7649
DOI - 10.1159/000365718
Subject(s) - medicine , paraganglioma , dysuria , cystectomy , urinary bladder , neuroblastoma , radiology , urinary system , urology , pathology , bladder cancer , cancer , anatomy , genetics , biology , cell culture
Paraganglioma of the urinary bladder is an uncommon clinical entity. Neuroblastoma of the urinary bladder is another rare tumor with only 7 reported cases, all in children. This report presents the case of a composite paraganglioma and neuroblastoma in a 45 year-old male who presented with dysuria and flank pain. On the computerized tomography scan, the bladder wall overlying the tumor was smooth and the mass had a large exophytic component. The initial diagnosis was paraganglioma on transurethral resection. Following partial cystectomy and bilateral pelvic lymph node dissection, pathology confirmed a composite tumor consisting of paraganglioma and neuroblastoma. To our knowledge, this is the first report of such a composite tumor involving the bladder.