Open AccessIncidentally-Discovered Squamous Cell Carcinoma after Endoscopic Sphincterotomy
Author(s) -
Tarek H. El-Ghazaly,
Chad Ellimoottil,
John S. Wheeler,
Larissa Bresler
Publication year - 2015
Publication title -
current urology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.476
H-Index - 13
eISSN - 1661-7657
pISSN - 1661-7649
DOI - 10.1159/000365710
Subject(s) - medicine , spinal cord injury , bladder cancer , urology , population , prostate cancer , cancer , surgery , spinal cord , environmental health , psychiatry
The association between the development of bladder cancer and chronic bladder irritation is well established in the literature. Chronic urinary tract irritation can be the result of bacterial infections, foreign bodies, trauma of repeated catheterization, neurogenic bladder, urolithiasis, or chronic bladder outlet obstruction, all which have been implicated in the pathogenesis of non-bilharzial squamous cell carcinoma of the bladder (SCC). With many of the aforementioned factors present in patients with spinal cord injury, several retrospective studies have demonstrated a 16-28 fold increased relative risk of bladder cancer, with SCC accounting for 10 times more cases of bladder cancer compared to the general population. In this report, we present the case of incidentally-discovered SCC of the bladder found within sphincter/prostate chips of a patient with neurogenic bladder due to spinal cord injury n clean intermittent catheterization ho underwent sphincterotomy with negative cystoscopic findings.