Activation of Microglia by Histamine and Substance P | Zendy

Jin Zhu | Zendy; Chen Qu | Zendy; Xiang Lü | Zendy; Shu Zhang | Zendy

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Activation of Microglia by Histamine and Substance P

Author(s) -

Jin Zhu,

Chen Qu,

Xiang Lü,

Shu Zhang

Publication year - 2014

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000363041

Subject(s) - microglia , histamine , substance p , chemistry , microbiology and biotechnology , proinflammatory cytokine , receptor , reactive oxygen species , immune system , tumor necrosis factor alpha , inflammation , immunology , biology , pharmacology , neuropeptide , biochemistry

Activated microglia perform many of the immune effector functions typically associated with macrophages. However, the regulators involved in microglial activation are not well defined. Because microglia play a pivotal role in immune surveillance of the CNS, we studied the effect of the neuromediators histamine and substance P on microglia.

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