Open AccessmiR-101 Promotes Breast Cancer Cell Apoptosis by Targeting Janus Kinase 2
Author(s) -
Lu Wang,
Linqiang Li,
Rui Guo,
Xuelian Li,
Ying Lu,
Xiaoxiang Guan,
Samuel Chege Gitau,
Leimin Wang,
Chaoqian Xu,
Baofeng Yang,
Hongli Shan
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000363010
Subject(s) - apoptosis , cancer research , breast cancer , viability assay , gene knockdown , mtt assay , transfection , cell growth , cancer , flow cytometry , microrna , janus kinase 2 , kinase , cell culture , chemistry , biology , microbiology and biotechnology , medicine , biochemistry , genetics , gene
microRNA-101 (miR-101) is down-regulated in several cancers. In this study, we explored the effects of dysregulated miR-101 on breast cancer cells and the underlying mechanisms.