Open AccessBiventricular Pacing Cardiac Contractility Modulation Improves Cardiac Contractile Function via Upregulating SERCA2 and miR-133 in a Rabbit Model of Congestive Heart Failure
Author(s) -
Bin Ning,
Xiaodan Qi,
Yingxiao Li,
Huiliang Liu,
Feifei Zhang,
Qin Chen
Publication year - 2014
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000358705
Subject(s) - heart failure , contractility , medicine , ejection fraction , ventricle , cardiology , cardiac function curve , cardiac output , diastole , stimulation , hemodynamics , anesthesia , blood pressure
To compare the effects of biventricular electrical pacing and conventional single-ventricular pacing for cardiac contractility modulation (CCM) on cardiac contractile function and to delineate the underlying molecular mechanisms.