Daintain/AIF-1 Plays Roles in Coronary Heart Disease via Affecting the Blood Composition and Promoting Macrophage Uptake and Foam Cell Formation
Author(s) -
Junhan Wang,
Yanying Zhao,
Wei Wang,
Zhongxia Du,
Dongjing Yan,
Chenhong Li,
Zhengwang Chen
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000350130
Subject(s) - foam cell , scavenger receptor , macrophage , oil red o , western blot , inflammation , pathology , medicine , lipoprotein , u937 cell , chemistry , cholesterol , biochemistry , in vitro , mesenchymal stem cell , adipogenesis , gene
Daintain/AIF-1 is an inflammatory polypeptide factor/allograft inflammatory factor 1 derived from macrophages. It is characterized in APOE(-/-) mice as a novel inflammatory factor associated with atherosclerosis. The purpose of this study was to characterize its function in human atherosclerosis.
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