Open AccessBaicalin Maintains Late-Stage Functional Cardiomyocytes in Embryoid Bodies Derived from Murine Embryonic Stem Cells
Author(s) -
Mingkai Tang,
Mengmeng Yin,
Ming Tang,
Huamin Liang,
Chong Jen Yu,
Xiancheng Zhang,
Haitao Luo,
Birte Baudis,
Moritz Haustein,
Markus Khalil,
Tomo Šarić,
Jürgen Hescheler,
Jun Xi
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000350127
Subject(s) - embryoid body , baicalin , embryonic stem cell , microbiology and biotechnology , induced pluripotent stem cell , stem cell , myocyte , cellular differentiation , biology , chemistry , biochemistry , high performance liquid chromatography , chromatography , gene
Low efficiency of cardiomyocyte (CM) differentiation from embryonic stem (ES) cells limits their therapeutic use. The objective of this study was to investigate the effect of baicalin, a natural flavonoid compound, on the in vitro cardiac differentiation of murine ES cells.