Open AccessPrediction of Sustained Virologic Response Based on Week 4 and Week 12 Response in Hepatitis C Virus Genotype 1 Patients Treated with Peginterferon and Ribavirin: Assessment in a Favorable <b><i>IL28B</i></b> Allele-Prevalent Area
Author(s) -
Hyun Jung Chung,
Jin Woo Lee,
Young Soo Kim,
Jung Il Lee
Publication year - 2013
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000345539
Subject(s) - ribavirin , medicine , gastroenterology , hepatitis c virus , cirrhosis , genotype , viral load , virus , virology , biology , gene , biochemistry
The aim of this study was to evaluate rapid virologic response (RVR) rate after peginterferon (PegIFN) and ribavirin (RBV) dual combination therapy in Korean hepatitis C virus (HCV) genotype 1 patients whose IL28B polymorphism is generally favorable. This study also assessed the value of RVR in predicting sustained virologic response (SVR).