Open AccessNative Soluble Carcinoembryonic Antigen Is Not Involved in the Impaired Activity of CD56<sup>dim</sup> Natural Killer Cells in Malignant Pleural Effusion
Author(s) -
Jing Qi,
Daling Li,
Jing Feng,
Sun Yang,
Yongxian Su,
Min Fang,
Zheng Tan,
Hong Shi,
Xiyun Yan,
Feili Gong,
Fang Zheng
Publication year - 2012
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000345214
Subject(s) - cytotoxic t cell , medicine , immune system , carcinoembryonic antigen , natural killer cell , immunology , flow cytometry , microbiology and biotechnology , biology , cancer , in vitro , biochemistry
Natural killer (NK) cells are lymphocytes of the innate immune system that play a crucial role in tumor immune surveillance. Accumulated data indicated that NK cells in the tumor microenvironment often display a suppressed function. However, the mechanism is not clear.