Thymic Stromal Lymphopoietin Over-Expressed in Human Atherosclerosis: Potential Role in Th17 Differentiation | Zendy

Jing Lin | Zendy; Wei Chun Chang | Zendy; Jiangchuan Dong | Zendy; Fengxiao Zhang | Zendy; Nilesh Mohabeer | Zendy; Kishan Kumar Kushwaha | Zendy; Lei Wang | Zendy; Yousu Su | Zendy; Hongcheng Fang | Zendy; Dazhu Li | Zendy

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Thymic Stromal Lymphopoietin Over-Expressed in Human Atherosclerosis: Potential Role in Th17 Differentiation

Author(s) -

Jing Lin,

Wei Chun Chang,

Jiangchuan Dong,

Fengxiao Zhang,

Nilesh Mohabeer,

Kishan Kumar Kushwaha,

Lei Wang,

Yousu Su,

Hongcheng Fang,

Dazhu Li

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000343369

Subject(s) - thymic stromal lymphopoietin , inflammation , immunology , immune system , cytokine , acquired immune system , stromal cell , umbilical vein , interleukin 17 , biology , microbiology and biotechnology , medicine , cancer research , in vitro , biochemistry

Adaptive immunity plays a critical role in atherosclerosis and T helper 17 (Th17) cells, a new T-cell lineage, are recently reported to be involved in atherosclerosis. However, the mechanism underlying Th17 inflammation in atherosclerosis remains largely unknown. Thymic stromal lymphopoietin (TSLP) is a novel IL-7-like cytokine and mainly responsible for Th2 inflammation in many inflammatory diseases.

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