Open AccessHuman Mesenchymal Stem Cells Reduce Lung Injury in Immunocompromised Mice but Not in Immunocompetent Mice
Author(s) -
Rebecca Lim,
Phillipa Louise Milton,
Sean V. Murphy,
Hayley Dickinson,
Sze Wah Samuel Chan,
Graham Jenkin
Publication year - 2012
Publication title -
respiration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.264
H-Index - 81
eISSN - 1423-0356
pISSN - 0025-7931
DOI - 10.1159/000343078
Subject(s) - medicine , mesenchymal stem cell , bleomycin , lung , immune system , stem cell , immunology , pathology , chemotherapy , biology , genetics
The immunomodulatory and immunosuppressive capacity of human mesenchymal stem cells (hMSC) is well recognized, but efficacies of hMSC in immunocompetent and immunocompromised animals have never been directly compared.