Open AccessResponse to Growth Hormone Therapy in Children with Noonan Syndrome: Correlation with or without <b><i>PTPN11</i></b> Gene Mutation
Author(s) -
JinHo Choi,
Beom Hee Lee,
Chang-Woo Jung,
Yoo-Mi Kim,
Hye Young Jin,
Jae-Min Kim,
Gu-Hwan Kim,
Jin Soon Hwang,
Sei Won Yang,
Jin Liu,
HanWook Yoo
Publication year - 2012
Publication title -
hormone research in paediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.816
H-Index - 89
eISSN - 1663-2826
pISSN - 1663-2818
DOI - 10.1159/000339677
Subject(s) - ptpn11 , noonan syndrome , medicine , short stature , endocrinology , kras , bone age , growth hormone deficiency , percentile , growth hormone , hormone therapy , hormone , cancer , colorectal cancer , statistics , mathematics , breast cancer
The objective of this study was to evaluate the efficacy of recombinant human growth hormone (rhGH) therapy and the influence of genotype on the response to rhGH therapy in children with Noonan syndrome (NS).