A Confidence Set Inference Method for Identifying SNPs That Regulate Quantitative Phenotypes
Author(s) -
Charalampos Papachristou,
Shili Lin
Publication year - 2012
Publication title -
human heredity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 62
eISSN - 1423-0062
pISSN - 0001-5652
DOI - 10.1159/000339178
Subject(s) - single nucleotide polymorphism , genetic association , confidence interval , inference , genome wide association study , framingham heart study , biology , computational biology , genetics , computer science , statistics , framingham risk score , mathematics , genotype , medicine , gene , artificial intelligence , disease , pathology
We introduce a family-based confidence set inference (CSI) method that can be used in preliminary genome-wide association studies to obtain confidence sets of SNPs that contribute a specific percentage to the additive genetic variance of quantitative traits.
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