Open AccessGenistein Stimulates Jejunal Chloride Secretion via Sex-dependent, Estrogen Receptor or Adenylate Cyclase Mechanisms
Author(s) -
Layla AlNakkash
Publication year - 2012
Publication title -
cellular physiology and biochemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000339053
Subject(s) - endocrinology , medicine , antagonist , adenylate kinase , histaminergic , basal (medicine) , estrogen receptor , forskolin , estrogen , chemistry , receptor , cancer , breast cancer , insulin
Daily subcutaneous injections with the phytoestrogen genistein, 600 mg/ kg genistein/day (600G) significantly increased intestinal chloride (Cl(-)) secretion (I(sc), µA/cm(2)) in C57BL/6J female and male murine jejunum after 1-2-weeks treatment.