4-1BB-mediated Signals Confer Protection Against Folic Acid-induced Nephrotoxicity | Zendy

Xiaozhong Li | Zendy; Jihong Dai | Zendy; Yuhua Qiu | Zendy; Xueguang Zhang | Zendy

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4-1BB-mediated Signals Confer Protection Against Folic Acid-induced Nephrotoxicity

Author(s) -

Xiaozhong Li,

Jihong Dai,

Yuhua Qiu,

Xueguang Zhang

Publication year - 2012

Publication title -

kidney and blood pressure research

Language(s) - Uncategorized

Resource type - Journals

eISSN - 1423-0143

pISSN - 1420-4096

DOI - 10.1159/000339022

Subject(s) - nephrotoxicity , immune system , kidney , cd3 , endocrinology , medicine , context (archaeology) , renal function , spleen , creatinine , kidney disease , monoclonal antibody , immunology , antibody , chemistry , biology , cd8 , paleontology

The role of co-stimulatory molecules in renal diseases has been previously examined, however, little is known about the role of 4-1BB in the context of renal diseases resulting from nonimmune-mediated tubulointerstitial fibrosis. Folic acid induced Nephrotoxicity (FAN) in mice was used to explore the role of 4-1BB in this setting.

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