Phylloquinone and Vitamin D Status: Associations with Incident Chronic Kidney Disease in the Framingham Offspring Cohort | Zendy

Conall M. O’Seaghdha | Zendy; ShihJen Hwang | Zendy; Rachel M. Holden | Zendy; Sarah L. Booth | Zendy; Caroline S. Fox | Zendy

Open Access

Phylloquinone and Vitamin D Status: Associations with Incident Chronic Kidney Disease in the Framingham Offspring Cohort

Author(s) -

Conall M. O’Seaghdha,

ShihJen Hwang,

Rachel M. Holden,

Sarah L. Booth,

Caroline S. Fox

Publication year - 2012

Publication title -

american journal of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 85

eISSN - 1421-9670

pISSN - 0250-8095

DOI - 10.1159/000339005

Subject(s) - medicine , albuminuria , kidney disease , quartile , endocrinology , vitamin d and neurology , population , creatinine , framingham risk score , risk factor , cohort , renal function , gastroenterology , disease , confidence interval , environmental health

Cardiovascular risk factors are associated with the development of chronic kidney disease (CKD), and CKD and vascular disease are etiologically linked. Evidence suggests deficiencies of vitamins D and K may adversely affect the cardiovascular system, but data from longitudinal studies are lacking. We hypothesized that deficiencies of vitamins D and K may be associated with incident CKD and/or incident albuminuria amongst members of the general population.

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