Mortality Associated with Dose Response of Erythropoiesis-Stimulating Agents in Hemodialysis versus Peritoneal Dialysis Patients
Author(s) -
Uyen Duong,
Kamyar KalantarZadeh,
Miklos Z. Molnar,
Joshua J. Zaritsky,
Isaac Teitelbaum,
Csaba P. Kövesdy,
Rajnish Mehrotra
Publication year - 2012
Publication title -
american journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 85
eISSN - 1421-9670
pISSN - 0250-8095
DOI - 10.1159/000335685
Subject(s) - medicine , hemodialysis , peritoneal dialysis , hazard ratio , kidney disease , proportional hazards model , gastroenterology , dialysis , poisson regression , anemia , nephrology , surgery , confidence interval , population , environmental health
Several studies have shown an association between erythropoietin-stimulating agent (ESA) responsiveness and mortality in chronic kidney disease (CKD) patients. In our present study, we examined the association between prescribed ESA dose and mortality in peritoneal dialysis (PD) and hemodialysis (HD) patients. We hypothesized that PD patients received lower ESA dose for the same achieved hemoglobin compared to HD patients and that ESA dose-mortality associations were different between PD and HD patients.
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