Neutrophil Activation in Severe, Early-Onset COPD Patients versus Healthy Non-Smoker Subjects in vitro: Effects of Antioxidant Therapy | Zendy

Javier Milara | Zendy; Gustavo Alberto San Juan | Zendy; Teresa Peiró | Zendy; Adela Serrano | Zendy; Julio Cortijo | Zendy

Open Access

Neutrophil Activation in Severe, Early-Onset COPD Patients versus Healthy Non-Smoker Subjects in vitro: Effects of Antioxidant Therapy

Author(s) -

Javier Milara,

Gustavo Alberto San Juan,

Teresa Peiró,

Adela Serrano,

Julio Cortijo

Publication year - 2011

Publication title -

respiration

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.264

H-Index - 81

eISSN - 1423-0356

pISSN - 0025-7931

DOI - 10.1159/000332834

Subject(s) - copd , medicine , neutrophil elastase , elastase , immunology , chemotaxis , pathogenesis , reactive oxygen species , acetylcysteine , oxidative stress , inflammation , antioxidant , chemistry , biochemistry , receptor , enzyme

Neutrophils and oxidative stress have been implicated in the pathogenesis of COPD. Severe, early-onset COPD is characterized by a rapid decline in the lung function at an early age; however, nothing is known about neutrophil activation in COPD patients.

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