Stimulation of Murine Intestinal Secretion by Daily Genistein Injections: Gender-dependent Differences | Zendy

Layla AlNakkash | Zendy; Lyn Batia | Zendy; Minoti Bhakta | Zendy; Amity Peterson | Zendy; Nathan Hale | Zendy; Ryan Skinner | Zendy; Steven Sears | Zendy; J C Jensen | Zendy

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Stimulation of Murine Intestinal Secretion by Daily Genistein Injections: Gender-dependent Differences

Author(s) -

Layla AlNakkash,

Lyn Batia,

Minoti Bhakta,

Amity Peterson,

Nathan Hale,

Ryan Skinner,

Steven Sears,

J C Jensen

Publication year - 2011

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000331736

Subject(s) - genistein , endocrinology , medicine , basal (medicine) , stimulation , forskolin , secretion , chemistry , insulin

The effect of daily injections with genistein (naturally occurring phytoestrogen) on intestinal chloride (Cl(-)) secretion was measured with Ussing chamber short circuit current (I(sc), μA/cm(2)), in C57BL/6J male and female mice, using 600 mg/kg genistein/day (600G), 300 mg/kg genistein/day (300G), 150 mg/kg genistein/day (150G) or genistein-free vehicle control (0G) for 1- or 2-weeks.

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