Open AccessInhibitory Effect of Unsaturated Fatty Acids on Saturated Fatty Acid-Induced Apoptosis in Human Pancreatic β-Cells: Activation of Caspases and ER Stress Induction
Author(s) -
Vlasta NěmcováFürstová,
R. F. L. James,
Jan Kovář
Publication year - 2011
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000329954
Subject(s) - unfolded protein response , oleic acid , stearic acid , palmitoleic acid , apoptosis , palmitic acid , saturated fatty acid , chemistry , fas ligand , fatty acid , microbiology and biotechnology , caspase , biochemistry , biology , programmed cell death , organic chemistry
In this study we have tested the effect of unsaturated fatty acids on the proapoptotic effects of saturated fatty acids in the human pancreatic β-cells NES2Y.