Open AccessEffect of a Chronic Cholesterol-rich Diet on Vascular Structure and Oxidative Stress in LDLR<sup>-/-</sup> Mice
Author(s) -
Benjamin Lauzier,
Stéphanie Delemasure,
Bertrand Collin,
Laurence Duvillard,
Franck Ménétrier,
Catherine Vergely,
JeanLouis Connat,
Luc Rochette
Publication year - 2011
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000325211
Subject(s) - ldl receptor , oxidative stress , medicine , endocrinology , cholesterol , receptor , chemistry , aorta , lipoprotein
There is conflicting evidence regarding the relationship between hypercholesterolemia and oxidative stress in vessels. To test the potential relationship, a mouse model of hypercholesterolemia was used.