Phenotypic and Differentiation Stability of Human Embryonic Stem Cell-Derived Osteoblasts | Zendy

Premjit Arpornmaeklong | Zendy; Michael J. Pressler | Zendy; Paul H. Krebsbach | Zendy

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Phenotypic and Differentiation Stability of Human Embryonic Stem Cell-Derived Osteoblasts

Author(s) -

Premjit Arpornmaeklong,

Michael J. Pressler,

Paul H. Krebsbach

Publication year - 2011

Publication title -

cells tissues organs

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.662

H-Index - 82

ISSN - 1422-6405

DOI - 10.1159/000324831

Subject(s) - embryonic stem cell , biology , microbiology and biotechnology , induced pluripotent stem cell , osteoblast , cellular differentiation , phenotype , cell culture , gene , in vitro , genetics

To ensure the efficiency and safety of transplanted human embryonic stem cell (hESC)-derived osteoblast-like cells (hESC-OS) for bone regeneration, this study was designed to determine the effects of continuous cell expansion on the osteoblastic differentiation stability, pluripotency, and tumorigenic potential of long-term expanded hESC-OS.

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