Open AccessPRO_10 – A New Tissue-Based Prognostic Multigene Marker in Patients with Early Estrogen Receptor-Positive Breast Cancer
Author(s) -
Andreas E. Moor,
Carmen Gutiérrez Guevara,
H. J. Altermatt,
Ryan J. Warth,
Rolf Jaggi,
Stefan Aebi
Publication year - 2011
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000323809
Subject(s) - breast cancer , medicine , estrogen receptor , oncology , stage (stratigraphy) , cancer , odds ratio , estrogen , gynecology , biology , paleontology
Clinicopathological and molecular factors determine the prognosis of breast cancer. PRO_10 is a prognostic score based on quantitative RT-PCR of 10 proliferation-associated genes obtained from formalin-fixed, paraffin-embedded breast cancer tissues. We revalidated PRO_10 in patients treated in a non-trial setting.